Spe is a python IDE with auto-indentation, auto completion, call tips, syntax coloring, syntax highlighting, class explorer, source index, auto todo list, sticky notes, integrated pycrust shell, python file browser, recent file browser, drag & drop, context help, ... Special is its blender support with a blender 3d object browser and its ability to run interactively inside blender. Spe ships with wxGlade (GUI designer), PyChecker (source code doctor) and Kiki (regular expression console). Spe is extensible with wxGlade.
You can get SPE from here.